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The Nencki Institute of Experimental Biology is a Polish scientific research organization and a part of Polish Academy of Sciences headquartered in Warsaw, Poland. Founded in 1918, it is a leading institution in the country in the field of neurobiology, molecular biology and biochemistry. == About the Institute == The Institute comprises laboratories and equipment for amongst others, modern confocal microscopy, scanning and flow cytometry, electron microscopy, behavioural testing and electrophysiology. Currently, the Institute is home to 40 laboratories organised into 4 departments, as well as 6 core facility laboratories forming the Neurobiology Centre established in 2013. The Institute's scientific teams conduct research in neurobiology, neurophysiology, and molecular biology. The experiments are interdisciplinary in character. The research concentrates on systems of varying complexity, from whole organisms through tissues, individual cells, cellular organelles to proteins and genes. The research topics mainly concentrate on determining signalling pathways whose disruption leads to the development of disease. As of January 1, 2014 the Nencki Institute has once again become the owner of the Mikołajki Research Station (). The Station is the site of research in the areas of aquatic and terrestrial ecosystem ecology, and environmental monitoring. The Station/Institute is empowered to bestow PhD and DSc doctoral degrees. The laboratories of the Nencki Institute are organised into 4 separate Departments: Cell Biology, Biochemistry, Molecular and Cell Neurobiology and Neurophysiology. There are also 6 other laboratories that constitute the Neurobiology Centre. The research conducted in the Departments of Neurophysiology and Molecular and Cell Neurobiology mainly deals with the cognitive functions of the Brain. The dominant theme is the plasticity of the nervous system under normal and pathological conditions. We study the effects of stroke and neurodegenerative diseases, epileptogenesis and the consequences of re-innervation, as well as emotional disturbances in humans. The research at the Department of Cell Biology is chiefly directed towards elucidating signalling cascades and regulatory mechanisms of gene expression involved in tumour transformation and the immune response, including the participation of membrane lipids in signal transfer by immunoreceptors, as well as the genetic regulation of cytoskeletal reorganisation. The Department of Biochemistry concentrates its research efforts on describing the molecular mechanisms of lipid-induced insulin resistance and type 2 diabetes, the regulation of calcium-mediated signal pathways, kinesine functioning, the role of mitochondria in the maintenance of cellular homeostasis and the development of pathologies, as well as the elucidation of the structure and function of intracellular ion channels. The Neurobiology Centre conducts interdisciplinary basic research as well as research on novel diagnostic and therapeutic methods in relation to the nervous system. This is conducted in collaboration with many institutes and universities in Warsaw as part of the Innovative Economy Operational Programme project entitled "Centre for Preclinical Research and Technology CEPT 2007-2013”. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nencki Institute of Experimental Biology」の詳細全文を読む スポンサード リンク
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